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2025 USA’s Top 5 Puppy Multivitamin Supplements: Vet-Reviewed, Growth-Focused Options to Support Bone, Brain & Immunity

Published on Thursday, August 21, 2025

Formulated for growing puppies to support healthy development, bone growth, cognitive function, and immune system maturation, puppy multivitamin supplements bring targeted nutrients that busy pet owners seek to complement a balanced diet. In United States, shoppers prioritize formulas with transparent ingredient lists (DHA, calcium/vitamin D balance, B-complex, antioxidants, and probiotics), palatable chewable delivery, and third-party or veterinary review. Convenience, clear dosing by weight, and regionally available brands also drive purchasing decisions—owners want safe, evidence-informed products that help bridge occasional dietary gaps without replacing high-quality puppy food.

Top Picks Summary

1. Best Taste & Broad Support

2. Best Budget Daily Vitamin

3. Best Premium Holistic Formula

4. Best Vet-Trusted Classic

5. Best Comprehensive Ingredient Blend

Top Picks Summary

  1. Zesty Paws 8-in-1 Multivitamin Bites for Puppies
  2. NaturVet VitaPet Puppy Daily Vitamins
  3. Pet Wellbeing Young Life Daily Multi for Puppies
  4. Nutri-Vet Multi-Vite Chewables for Puppies
  5. PetHonesty 10-in-1 Multivitamin for Puppies
1
BEST TASTE & BROAD SUPPORT

Zesty Paws 8-in-1 Multivitamin Bites for Puppies

Zesty Paws 8-in-1 Multivitamin Bites for Puppies
🏠 Local Product

Zesty Paws 8-in-1 Multivitamin Bites for Puppies ranks as a best-in-class choice because its highly palatable soft-bite format and focused eight-target blend deliver puppy-specific nutrients (skin & coat, digestion, immunity and more) with broad retail availability and competitive price-per-dose. Compared with the other options on this list, Zesty Paws balances comprehensive benefits and affordability, making it a practical choice for owners who want a widely tested, easy-to-dose daily supplement during early growth.

4.6
★★★★☆
  • Shiny coat boost

  • Puppy-approved taste

  • Shiny coat boost

  • Puppy-approved taste

Review Summary

90%

"Users generally praise the taste and convenience; many report improvements in coat, digestion and energy after regular use, though a minority mention variable effectiveness or mild digestive upset."

  • Easy soft chews

  • 8-in-1 formula supports skin, coat, digestion and immunity

  • Easy soft chews

  • 8-in-1 formula supports skin, coat, digestion and immunity

Self-Improvement & Personal Growth

Recreational Enjoyment

Time-Saving Convenience

Zesty Paws 8-in-1 Multivitamin Bites for Puppies ranks as a best-in-class choice because its highly palatable soft-bite format and focused eight-target blend deliver puppy-specific nutrients (skin & coat, digestion, immunity and more) with broad retail availability and competitive price-per-dose. Compared with the other options on this list, Zesty Paws balances comprehensive benefits and affordability, making it a practical choice for owners who want a widely tested, easy-to-dose daily supplement during early growth.

  • Shiny coat boost

  • Puppy-approved taste

  • Easy soft chews

  • 8-in-1 formula supports skin, coat, digestion and immunity

  • Soft, chicken-flavored chews that puppies generally find palatable

  • Shiny coat boost

  • Puppy-approved taste

  • Easy soft chews

  • 8-in-1 formula supports skin, coat, digestion and immunity

  • Soft, chicken-flavored chews that puppies generally find palatable

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$18-30 USD

2
BEST BUDGET DAILY VITAMIN

NaturVet VitaPet Puppy Daily Vitamins

NaturVet
🏠 Local Product

NaturVet VitaPet Puppy Daily Vitamins is a market-leading, budget-friendly option that provides straightforward multivitamin support with joint and general health ingredients, appealing to cost-conscious owners who need dependable daily coverage. While less feature-packed than Zesty Paws or PetHonesty's higher-count formulas, NaturVet's lower price and long retail presence make it a sensible foundational supplement for growing puppies.

4.2
★★★★☆
  • Immune daily help

  • Herbal-friendly formula

  • Immune daily help

  • Herbal-friendly formula

Review Summary

82%

"Buyers appreciate the low price and chewability and some report modest benefits, but reviews note inconsistent results for different puppies and concerns about artificial ingredients."

  • No-fuss dosing

  • Daily tablet with essential vitamins and minerals formulated for growth

  • No-fuss dosing

  • Daily tablet with essential vitamins and minerals formulated for growth

Self-Improvement & Personal Growth

Time-Saving Convenience

NaturVet VitaPet Puppy Daily Vitamins is a market-leading, budget-friendly option that provides straightforward multivitamin support with joint and general health ingredients, appealing to cost-conscious owners who need dependable daily coverage. While less feature-packed than Zesty Paws or PetHonesty's higher-count formulas, NaturVet's lower price and long retail presence make it a sensible foundational supplement for growing puppies.

  • Immune daily help

  • Herbal-friendly formula

  • No-fuss dosing

  • Daily tablet with essential vitamins and minerals formulated for growth

  • Includes colostrum and antioxidants to support immune development

  • Immune daily help

  • Herbal-friendly formula

  • No-fuss dosing

  • Daily tablet with essential vitamins and minerals formulated for growth

  • Includes colostrum and antioxidants to support immune development

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$12-20 USD

3
BEST PREMIUM HOLISTIC FORMULA

Pet Wellbeing Young Life Daily Multi for Puppies

Pet Wellbeing Young Life Daily Multi for Puppies

Pet Wellbeing Young Life Daily Multi is positioned as a premium UK-formulated option emphasizing well-dosed, bioavailable vitamins and omega blends tailored to developmental stages, which helps justify its higher price compared with mass-market brands. It stands out technically by focusing on quality ingredients and targeted growth support, appealing to owners seeking vet-grade formulations rather than the cheapest daily option.

4.7
★★★★☆
  • Complete daily support

  • Omega-rich shine

  • Complete daily support

  • Omega-rich shine

Review Summary

93%

"Customers frequently report noticeable improvements in coat, digestion and energy and like the more natural ingredient list; satisfaction is high though some find it pricier than alternatives."

  • Tail-wagging flavor

  • Organic and highly bioavailable vitamins with chelated minerals for absorption

  • Tail-wagging flavor

  • Organic and highly bioavailable vitamins with chelated minerals for absorption

Self-Improvement & Personal Growth

Recreational Enjoyment

Pet Wellbeing Young Life Daily Multi is positioned as a premium UK-formulated option emphasizing well-dosed, bioavailable vitamins and omega blends tailored to developmental stages, which helps justify its higher price compared with mass-market brands. It stands out technically by focusing on quality ingredients and targeted growth support, appealing to owners seeking vet-grade formulations rather than the cheapest daily option.

  • Complete daily support

  • Omega-rich shine

  • Tail-wagging flavor

  • Organic and highly bioavailable vitamins with chelated minerals for absorption

  • Contains probiotics and digestive enzymes to support gut health

  • Complete daily support

  • Omega-rich shine

  • Tail-wagging flavor

  • Organic and highly bioavailable vitamins with chelated minerals for absorption

  • Contains probiotics and digestive enzymes to support gut health

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$40-60 USD

4
BEST VET-TRUSTED CLASSIC

Nutri-Vet Multi-Vite Chewables for Puppies

Nutri-Vet Multi-Vite Chewables for Puppies
🏠 Local Product

Nutri-Vet Multi-Vite Chewables for Puppies offers a veterinarian-friendly, no-frills chewable that prioritizes consistent dosing, affordability, and clinic availability, making it a dependable choice for routine supplementation and multi-pet households. It is typically less complex than PetHonesty or Zesty Paws but often undercuts them on price while maintaining veterinary brand credibility and wide distribution.

4.5
★★★★☆
  • Trusted vet staple

  • Puppy-friendly chew

  • Trusted vet staple

  • Puppy-friendly chew

Review Summary

88%

"Owners like the palatable chewables and steady multivitamin support; a minority say results are subtle or that a few puppies resist the flavor."

  • Growth nutrient mix

  • Veterinarian-formulated chewables delivering essential vitamins and minerals

  • Growth nutrient mix

  • Veterinarian-formulated chewables delivering essential vitamins and minerals

Time-Saving Convenience

Self-Improvement & Personal Growth

Recreational Enjoyment

Nutri-Vet Multi-Vite Chewables for Puppies offers a veterinarian-friendly, no-frills chewable that prioritizes consistent dosing, affordability, and clinic availability, making it a dependable choice for routine supplementation and multi-pet households. It is typically less complex than PetHonesty or Zesty Paws but often undercuts them on price while maintaining veterinary brand credibility and wide distribution.

  • Trusted vet staple

  • Puppy-friendly chew

  • Growth nutrient mix

  • Veterinarian-formulated chewables delivering essential vitamins and minerals

  • Supports bone, joint and immune development during puppy growth

  • Trusted vet staple

  • Puppy-friendly chew

  • Growth nutrient mix

  • Veterinarian-formulated chewables delivering essential vitamins and minerals

  • Supports bone, joint and immune development during puppy growth

Order Now

$15-25 USD

5
BEST COMPREHENSIVE INGREDIENT BLEND

PetHonesty 10-in-1 Multivitamin for Puppies

PetHonesty 10-in-1 Multivitamin for Puppies
🏠 Local Product

PetHonesty 10-in-1 Multivitamin for Puppies positions itself as a comprehensive, technically dense option by combining vitamins with probiotics and greens to offer broader coverage in a single product, which can deliver high perceived value despite a higher cost-per-serving. Compared to simpler, cheaper brands like NaturVet or Nutri-Vet, PetHonesty is geared toward owners who prefer an all-in-one approach to maximize nutritional coverage during critical puppy development.

4.6
★★★★☆
  • Multi-benefit punch

  • Probiotic boost

  • Multi-benefit punch

  • Probiotic boost

Review Summary

89%

"Most users report visible improvements in coat, skin and overall vitality and praise the taste, though some mention a strong smell or higher cost compared with basic multivitamins."

  • Treat-like chew

  • 10-in-1 formula including DHA, probiotics and antioxidants for overall development

  • Treat-like chew

  • 10-in-1 formula including DHA, probiotics and antioxidants for overall development

Self-Improvement & Personal Growth

Recreational Enjoyment

PetHonesty 10-in-1 Multivitamin for Puppies positions itself as a comprehensive, technically dense option by combining vitamins with probiotics and greens to offer broader coverage in a single product, which can deliver high perceived value despite a higher cost-per-serving. Compared to simpler, cheaper brands like NaturVet or Nutri-Vet, PetHonesty is geared toward owners who prefer an all-in-one approach to maximize nutritional coverage during critical puppy development.

  • Multi-benefit punch

  • Probiotic boost

  • Treat-like chew

  • 10-in-1 formula including DHA, probiotics and antioxidants for overall development

  • Grain-free soft chews made with natural ingredients and no artificial flavors

  • Multi-benefit punch

  • Probiotic boost

  • Treat-like chew

  • 10-in-1 formula including DHA, probiotics and antioxidants for overall development

  • Grain-free soft chews made with natural ingredients and no artificial flavors

Order Now

$25-40 USD

What research and veterinary guidance say about puppy multivitamins

Scientific research and veterinary nutrition guidance indicate that specific nutrients can support areas of puppy growth when dietary intake is insufficient or when a breeder or vet identifies a need. Key nutrients often found in puppy multivitamins—DHA for early brain development, balanced calcium and vitamin D for bone formation, B vitamins for energy metabolism, antioxidants for immune support, and probiotics for digestive health—have been studied in canines and other mammals. Veterinary bodies emphasize targeted supplementation guided by diet assessment and weight-based dosing rather than routine broad-spectrum use for every puppy.

DHA (an omega-3 fatty acid) has been associated with improved learning and visual development in young mammals; formulas with puppy-appropriate DHA levels are included to support cognitive development.

Calcium and vitamin D are essential to healthy bone growth; supplementation should be balanced and dosed appropriately for breed and growth rate to avoid skeletal issues.

B-complex vitamins support energy metabolism and nervous system function; deficiencies can show as poor growth or coat condition.

Antioxidants (vitamins A, C, E and trace minerals) contribute to immune system maturation and overall cellular health.

Probiotics and digestive enzymes in some multivitamins can help reduce gastrointestinal upset during diet transitions, but probiotic strains and doses matter for effectiveness.

Veterinary nutrition guidelines (including position statements from major vet associations) recommend supplementing only when diets are inadequate or when a veterinarian identifies a specific need; supplements do not replace a complete, balanced puppy diet.

In the American market for 2025, these five options represent a range of delivery styles and ingredient focuses to support growing puppies: Zesty Paws 8-in-1 Multivitamin Bites for Puppies, NaturVet VitaPet Puppy Daily Vitamins, Pet Wellbeing Young Life Daily Multi for Puppies, Nutri-Vet Multi-Vite Chewables for Puppies, and PetHonesty 10-in-1 Multivitamin for Puppies. For most American puppy owners looking for a broadly balanced, palatable formula with wide availability and vet-facing reviews, Zesty Paws 8-in-1 Multivitamin Bites for Puppies is the best overall choice on this list; NaturVet VitaPet and Nutri-Vet are solid budget-friendly alternatives, while Pet Wellbeing Young Life and PetHonesty offer focused ingredient profiles for targeted needs. We hope you found the guidance you were looking for — you can refine or expand your search by weight, ingredient (for example DHA or probiotics), breed size, or retailer to find the ideal match for your puppy.

Discover More
  • Daily Multivitamin Supplements for Dogs
  • Senior Multivitamin Supplements for Dogs
  • Skin and Coat Vitamin Supplements for Dogs
  • Immune and Antioxidant Vitamin Supplements for Dogs
  • Mineral and Electrolyte Blends for Dogs
  • Prenatal and Lactation Vitamin Supplements for Dogs
  • Single Vitamin Supplements for Dogs

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